Hong Kan Selected Research

Human Immunodeficiency Virus Proteins

3/2009	Dilated cardiomyopathy in transgenic mice expressing HIV Tat.
12/2008	CXCR4 receptor antagonist blocks cardiac myocyte p38 MAP kinase phosphorylation by HIV gp120.
1/2006	iPLA2 inhibitor blocks negative inotropic effect of HIV gp120 on cardiac myocytes.

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Hong Kan Research Topics

Disease

5	Cardiomyopathies (Cardiomyopathy) 03/2009 - 01/2004
2	Heart Failure 01/2022 - 12/2008
2	Cardiac Arrhythmias (Arrythmia) 01/2022 - 10/2009
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 12/2015
2	AIDS-Related Complex (ARC) 01/2015 - 01/2014
2	Pneumonia (Pneumonitis) 01/2014 - 01/2013
1	Hyperthermia 02/2022
1	Wounds and Injuries (Trauma) 02/2022
1	Bacterial Infections (Bacterial Infection) 02/2022
1	Vascular Remodeling 01/2022
1	Alcoholism (Alcohol Abuse) 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Hemiplegia (Spastic Hemiplegia) 01/2022
1	Hepatitis 01/2022
1	Inflammation (Inflammations) 01/2022
1	Neoplasms (Cancer) 01/2022
1	Paralysis (Palsy) 01/2022
1	Paraplegia (Spastic Paraplegia) 01/2022
1	Peripheral Vascular Diseases (Peripheral Vascular Disease) 01/2022
1	Weight Loss (Weight Reduction) 11/2021
1	Obesity 11/2021
1	Silicosis 11/2020
1	Stroke (Strokes) 07/2018
1	Hyperglycemia 02/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2014
1	Cardiomegaly (Heart Hypertrophy) 02/2012
1	Lipodystrophy 10/2011
1	Weight Gain 10/2011
1	Carcinogenesis 10/2011
1	Hypertension (High Blood Pressure) 10/2011
1	Infections 10/2011
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2011
1	Ventricular Dysfunction 03/2009
1	Bradycardia 03/2009
1	HIV Infections (HIV Infection) 12/2008

Drug/Important Bio-Agent (IBA)

3	Human Immunodeficiency Virus ProteinsIBA 03/2009 - 01/2006
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 03/2009
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2012
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 10/2011
2	belimumabIBA 01/2020 - 12/2015
2	MetalsIBA 01/2015 - 01/2014
1	Anti-Bacterial Agents (Antibiotics)IBA 02/2022
1	HydrogelsIBA 02/2022
1	Opioid Analgesics (Opioids)IBA 01/2022
1	AntioxidantsIBA 01/2022
1	EnzymesIBA 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	NitratesIBA 01/2022
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	NitritesIBA 01/2022
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2022
1	Antipsychotic Agents (Antipsychotics)IBA 01/2022
1	Anti-Anxiety Agents (Anxiolytics)IBA 01/2022
1	Short-Acting InsulinIBA 01/2022
1	Orlistat (Xenical)FDA Link 11/2021
1	Naltrexone (ReVia)FDA LinkGeneric 11/2021
1	Topiramate (Topamax)FDA LinkGeneric 11/2021
1	Bupropion (Wellbutrin)FDA LinkGeneric 11/2021
1	Liraglutide FDA Link 11/2021
1	Phentermine (Adipex-P)FDA LinkGeneric 11/2021
1	QuartzIBA 11/2020
1	Dobutamine FDA LinkGeneric 07/2018
1	galactomannanIBA 02/2017
1	Air Pollutants (Pollutants, Air)IBA 06/2014
1	Oxidants (Oxidizing Agents)IBA 01/2014
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2013
1	Vasoconstrictor AgentsIBA 01/2013
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2013
1	Insulin ReceptorIBA 02/2012
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 02/2012
1	ArsenicIBA 10/2011
1	Cyclic NucleotidesIBA 10/2009
1	HR 580IBA 03/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2009
1	Glucose (Dextrose)FDA LinkGeneric 01/2009
1	p38 Mitogen-Activated Protein KinasesIBA 01/2004

Therapy/Procedure

2	Therapeutics 12/2015 - 12/2008
1	Drug Therapy (Chemotherapy) 11/2021